Ordering Recommendation

Identify individuals at increased risk for statin-related muscle toxicity.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or pink (K2EDTA), or yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or serum. Heparinized specimens. Frozen specimens in glass collection tubes.

Remarks
Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring

Performed

Mon, Thu

Reported

5-10 days

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

81328

Components

Component Test Code* Component Chart Name LOINC
2008427 SLCO1B1, 1 Variant, Specimen 66746-9
2008428 SLCO1B1, 1 Variant,*5 Genotype 93412-5
3016893 EER SLCO1B1 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Simvastatin myotoxicity assay
  • Statin-induced myopathy assay
SLCO1B1, 1 Variant